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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Sirolimus
Research Papers that Mention the Interaction
“In non-infected cells S increased translational controlled tumor protein (TCTP) and phosphatase and tensin homolog (PTEN) proteins while M inhibited mammalian target of rapamycin (mTOR) and TCTP.”
Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy“Under nitrogen fertilization, Leu and Met accumulated in the green morph enhanced the target of rapamycin (TOR) signaling pathway, which consequently increased fecundity by promoting vitellogenin synthesis.”
Differential accumulation of leucine and methionine in red and green pea aphids leads to different fecundity in response to nitrogen fertilization.“ RPM potently inhibited platelet-derived growth factor (PDGF) (IC50=5×10-9 M ) and basic fibroblast growth factor (bFGF) (IC50=8×10-10 M)-induced VSMC DNA synthesis.”
“Overall, rapamycin showed cytocidal effects at a high concentration of 10−5 M , whereas imatinib did not.”
Different Responses of Neointimal Cells to Imatinib Mesylate and Rapamycin Compared with Normal Vascular Smooth Muscle Cells“Phenylalanine and methionine interfered in rapamycin production by unknown mechanisms.”
“ABSTRACT In a chemically defined medium, l-methionine decreased production of rapamycin and increased that of demethylrapamycin.”
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