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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Methionine
drug:
Savolitinib
Research Papers that Mention the Interaction
“ Volitinib demonstrated strong antitumor activity in PDX models with MET and phosphorylated MET (pMET) overexpression.”
Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer“In vitro, savolitinib inhibits MET phosphorylation with nanomolar potency, which correlates with blockade of PI3K/AKT and MAPK signaling as well as MYC down-regulation.”
“The activity of savolitinib was strongly asso ciated with the presence of MET alterations in the tumour.”
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