Possible Interaction: Methionine and Proline

“However, only deviations of proline and methionine may be judged as imbalances, and lowering in composition may be considered.”

“At the reported salinity‐adaptive bio‐accumulation of 1 M and above, proline could considerably decrease the T m and partially counteract the effect of sodium chloride and spermidine on DNA stability.”

“Certain other amino acids (L-valine, L-alanine, L-methionine , L-phenylalanine, L-tryptophan and L-hydroxyproline) significantly stimulated proline uptake.”

“ Methionine strongly inhibits proline and lysine uptake, which is significantly inhibited by their analogs hydroxiproline and arginine, respectively.”

“Estradiol-17beta demonstrated a time- and dose-dependent reduction of proline transport; at 10- M , transport of proline was decreased by 50 percent.”

“During differentiation the taurine, glutamic acid, GABA, glutamine, aspartic acid, glycine arginine, methionine and histidine levels increase while proline.”

“By competitively excluding proline from N 1 by adding methionine , it was possible to shift the uptake pattern of proline toward that of betaine.”

“ Proline was used as inhibitor of the transport of glycine and methionine.”

“The probable mechanism operating to produce this effect is suggested by the work ofWiseman (1955) who showed … mono-amino-mono-carboxylic acids compete for the concentrating mechanism of the hamster small intestine and that methionine completely inhibits the … of glycine, L-proline and L-histidine when … in equimolecular amounts.”

“The presence of proline following methionine in a protein sequence increased the modification rate as well.”