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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Prazosin
Research Papers that Mention the Interaction
“ PZN increased force 4% at 10-6 M and 18% at 10-4M.”
Hemodynamic effects of prazosin in chronic heart failure.“Normetadrenaline- and metadrenaline (3 × 10-5 M each)-induced aortic contractions were strongly inhibited by prazosin (10-8 M; an α1-adrenoceptor antagonist) and BMY 7378 (10-8-10-7 M; a selective α1D-adrenoceptor antagonist).”
Normetadrenaline and metadrenaline induce rat thoracic aorta/prostate contraction via α1D/1A-adrenoceptor stimulation.“2 At concentrations between 10−6 m and 10−5 m, prazosin produced a concentration‐dependent decrease in the maximum upstroke velocity (V̇max) and a progressive lengthening of the action potential duration at 50% (APD50) and 90% (APD90) of repolarization.”
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