Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Methionine and Phospholipids

supplement:

Methionine

Research Papers that Mention the Interaction

Substitution of Asn-1 with Met caused a reduction in enzymatic activity and membrane-damaging activity of PLA(2) toward phospholipid vesicles , while sphingomyelin exerted an inhibitory effect on the biological activities of native and mutated PLA(2).
Chemistry and physics of lipids  •  2011  |  View Paper
At a higher concentration of 10−7 M , this phospholipid induced more rapid, but not greater, contraction.
Lipids  •  2006  |  View Paper
The uptake of methionine and transfer of methyl group to phospholipid in the cells by methionine were remarkably higher than those by S-adenosylmethionine.
Life sciences  •  1985  |  View Paper
1 H-NMR resonance of both the methionine methyl group (met-27) and the aromatic envelope of glucagon are broadened by the phospolipid , indicating that the C-terminal region and the aromatic residues are involved in the interaction with the phospholipid.
Biochimica et biophysica acta  •  1983  |  View Paper
A significant incorporation of methyl groups into phospholipids occurred not only with methionine but also with SAM.
The Biochemical journal  •  1982  |  View Paper
A tenfold increase of I4C incorporated into phospholipids was found in both groups after methionine was added.
The British journal of nutrition  •  1980  |  View Paper
The rate of phosphatidylcholine formation via phospholipid N-methylation approximately doubled when L-methionine was added at concentrations similar to that in rat plasma.
The Journal of biological chemistry  •  1975  |  View Paper
Methionine lowers the concentrations of serum triglycerides and phospholipids only slightly but substantially lowers serum cholesterol concentration.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1962  |  View Paper
It is suggested that a definite increase in phospholipide turnover following a single large dose of choline or methionine may indicate fatty infiltration of the liver, and perhaps provide an indication of the need for treatment with lipotropic substances.
Gastroenterology  •  1950  |  View Paper
Indeed, in experimental animals with fatty infiltration of the liver induced by diet, it has been shown by the use of radiophosphorus that choline or methionine will cause an increase in the phospholipide turnover in the liver (4, 5).
The Journal of clinical investigation  •  1950  |  View Paper