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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Phentolamine
Research Papers that Mention the Interaction
“There was a partial reversal of the pain evoked by 10−5 M NE after pretreatment with phentolamine (NE 10−5 M prephentolamine versus normal saline P=0.02, NE 10−5 M postphentolamine versus normal saline P=0.054).”
Local Administration of Norepinephrine in the Stump Evokes Dose-dependent Pain in Amputees“The results indicated that 10−5 M of NA inhibits the chemotaxis of lymphocytes from both the immunocompetent organs studied, and that this effect is blocked by either propranolol (10−6 M) or phentolamine (10−5 M).”
Noradrenaline and its end metabolite 3-methoxy-4-hydroxyphenylglycol inhibit lymphocyte chemotaxis: Role of alpha- and beta-adrenoreceptors“However, use of phentolamine at 10−5 M , but not at lower concentrations of the drug, resulted in complete inhibition of SCN−-induced contractions.”
“being observed at 10−3 M. The cerebrovascular constriction produced by dopamine 10−5 M ) could be significantly attenuated by the concomitant perivascular administration of phentolamine (10−6 M) or methysergide (10−6 M).”
“The α and β adrenergic blocking agents phentolamine and propranolol) at 10 −5 M acted to antagonize cyclic AMP accumulation in response to NE in all brain regions, while at 10 −6 M the α blocker was ineffective in the cerebral cortex and less effective in the medial hypothalamus.”
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