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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Phenobarbital
Research Papers that Mention the Interaction
“The presence of alcohol (≤1.96 × 10–2 M ) can increase the proportion of free phenobarbital and shorten the half-life and storage time of phenobarbital in the blood, thereby enhancing its bioactive efficacy.”
Molecular spectroscopic studies examining the interactions between phenobarbital and human serum albumin in alcohol consumption“Tumour promotion by PB led to significant increases in the number of preneoplastic and neoplastic lesions in liver of both wild‐type and c‐met knockout mice, with only minor differences in response.”
Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c‐Met“Inclusion of PB in the culture medium markedly enhanced the CBA reductase activity while L-methionine , which elevates the cellular glutathione (GSH) level, suppressed the stimulatory effect of PB.”
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