Possible Interaction: Methionine and Pentobarbital

“Treatment with both pentobarbital (10−4 M) and dihydropyridine Ca2+ antagonists ( 10−9 M ) shifted the CaCl2 concentration‐response curves to the right significantly compared with those after treatment with the Ca2+ antagonists and pentobarbital alone.”

“Intravenous administration of leucine and methionine enkephalin (10, 30 and 100 micrograms/kg) resulted in a dose dependent and transient decline in mean arterial blood pressure in pentobarbital anesthetized cats.”

“ Pentobarbitone (10−5 to 10−3 M) decreased the basal tone of vascular smooth muscle of goat middle cerebral artery in a dose‐dependent manner as well as relaxing established contractions induced by noradrenaline (NA) ( 10−5 M ), 5‐hydroxytryptamine (5‐HT) (10−5 M) and KCl(120 mM).”