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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
supplement:
Oxytocin
Research Papers that Mention the Interaction
“The TREK‐1 blocker l‐methionine enhanced oxytocin contraction in Singleton‐Term and twin pregnant uterus, and reversed the decreases in contraction in uterine strips exposed to prolonged stretch.”
Adaptive reduction of human myometrium contractile activity in response to prolonged uterine stretch during term and twin pregnancy. Role of TREK‐1 channel“… oxytocin … M significantly reduced motility index (estimate [standard error]: −0.771 [0.270] square root units, P = 0.005 and −0.697 [0.293], P = 0.….241 [2.189], P = 0.05, respectively) compared with control group, whereas pretreatment with oxytocin 10−10 M did not significantly attenuate contractions.”
“The intrathecal administration of 20 μl of a 10⁻⁵ M solution of a specific oxytocin antagonist strongly reduced the PVN effects, and 20 μl of 10⁻⁶ M naloxone significantly reduced the RMg suppression of receptive field responses.”
Functional interactions between the paraventricular hypothalamic nucleus and raphe magnus. A comparative study of an integrated homeostatic analgesic mechanism“Dynorphin (1–17) 10−7 M ) increased the electrically evoked release of VP and OT , while 10−6 M had a significant, somewhat less pronounced stimulatory effect only on VP, but not on OT release.”
“At high concentrations (10–8 and 5 10–8 M), oxytocin induced conduction blocks and the size of inexcitable areas was increased, concomitantly with an increase in muscle contractures.”
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