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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Nortriptyline
Research Papers that Mention the Interaction
“Tricyclic antidepressants nortriptyline , chlorimipramine, protiptyline, imipramine and desipramine at a concentration of 10−3 M caused 60–80% inhibition of PDE activity.”
Effect of phenothiazine neuroleptic drugs and tricyclic antidepressants on phosphodiesterase activity in rat cerebral cortex“In the presence of nortriptyline (10 −6 M), the responses to field stimulation at low frequencies were potentiated and the responses to (−)-noradrenaline were unaltered by phentolamine (5 × 10 −9 M ) and yohimbine (5 × 10 −7 M ).”
“2 Amitriptyline, nortriptyline , protriptyline, desipramine and imipramine were found to inhibit ATPases at concentrations of 10−5 m and above.”
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