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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Nicorandil
Research Papers that Mention the Interaction
“Addition of 10−5 M nicorandil to medium supplemented with 10% serum resulted in a decrease of the net cholesteryl ester content by 18±1%, while cellular free cholesterol content was the same as control.”
Effects of nicorandil on cell proliferation and cholesteryl ester accumulation in arterial smooth muscle cells in culture“Furthermore, nicorandil 3 × 10 -6M potentiated the increase in the tissue level of cyclic AMP caused by ISO 3 × 10-7 M , whereas the nicorandil-induced increase in cyclic GMP levels were not affected by ISO.”
“5 The negative inotropic effect produced by 3 × 10−4 m nicorandil was greatly reduced by 10−2 m tetraethylammonium, whereas the increase in cyclic GMP produced by this concentration of nicorandil was not significantly changed.”
“The peak tension of phasic contractions was reduced by 10−6 M and phasic contractions were eliminated by 10−4M of nicorandil.”
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