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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Methionine
drug:
Lapatinib
Research Papers that Mention the Interaction
“A positive crosstalk was shown between HER2 and MET , each of which increased resistance to lapatinib and/or cisplatin.”
FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation“Immunoblotting analysis indicated that phosphorylation of HER2, EGFR, MET , AKT, and extracellular signal-regulated kinase was inhibited by lapatinib and presumably led to cell-cycle arrest as observed with flow cytometry.”
“Western blot analyses showed that combining foretinib with erlotinib or lapatinib effectively decreased the phosphorylation of MET , HER1, HER2, HER3, AKT, and ERK in these cells.”
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