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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Methionine
drug:
Geldanamycin
Research Papers that Mention the Interaction
“Therapeutic approaches that block MET signaling are being studied, and include the use of: small interference RNA, Geldanamycin , competitive HGF homologues, decoy receptors, and direct MET inhibitors such as K252a, SU11274, PHA665752 and PF2341066.”
MET molecular mechanisms and therapies in lung cancer“In our study, we found that GA decreased the level of MET expression and inhibited the chemotaxis of RMS cells toward the hepatocyte growth factor gradient.”
“Inhibitors of MEK1 (U0126) and HSP90 (geldanamycin) significantly reduced MSV-MDCK-INV cell motility and pseudopod expression, and geldanamycin treatment inhibited Met phosphorylation and induced the expression of actin stress fibers.”
Tumor Cell Pseudopodial Protrusions
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