Possible Interaction: Methionine and Colforsin

“Exposure of the HT29 cells to 10−5 M forskolin in the early stages of growth induction (within 12 h from FCS addition or within 14 h from insulin treatment) resulted in a significant inhibition of DNA synthesis and a delayed entry in the S phase.”

“ Forskolin , over a concentration range of 10−7–10−5 M , dose-dependently increased short circuit current (Isc) and transmural potential differences (Vms).”

“Nicorandil 3 × 10 M also potentiated the relaxations induced by forskolin 3 × 10 9-10 6M and dibutylyl-cyclic AMP 3 × 10-6-3 × 10 -4M.”

“Pretreatment with 10−6 M PMA for 30 min did not affect PTH receptor binding but significantly augmented a cAMP responsiveness to 10−5 M forskolin and 1 ug/ml cholera toxin.”

“ Forskolin (10−9 M) potentiated the vasodilation caused by 10−6 M NECA, thus implicating adenylate cyclase activation during NECA-induced vasodilation and providing further support for involvement of the A2 receptor.”

“ M ) inhibited the effect of forskolin (combined with IBMX) in a concentration-dependent and spiroperidol-sensitive manner, and did not modify the action of dibutyrylcyclic AMP.”