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“Proportions of IFN-γ negative CD4+ expressing IL-2 , Perforin, or TNF-α to Con M were significantly higher (5 of 7 functional profiles) than the corresponding IFN-γ positive CD4+ (0 of 7) T-cell phenotype, p = 0.02; Fisher’s Exact test.”
“Heroin and M significantly increased production of IL-1beta, IL-2 , TNF-alpha and IFN-gamma at 3, 20 and 40 min from treatment, peaking at 20 min, though the effect was very brief.”