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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methamphetamine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“The present study shows that pretreatment with yohimbine dose-dependently decreased the ambulatory hyperactivities induced by METH (2 mg/kg) in mice.”
Role of hippocampal α2A-adrenergic receptor in methamphetamine-induced hyperlocomotion in the mouse“A lower 3.0 mg/kg dose of yohimbine increased methamphetamine-appropriate responding when given together with low 0.1–0.3 mg/kg doses of methamphetamine.”
“The alpha-2 NE antagonist, yohimbine , also partially generalized to methamphetamine and blocked the discriminative-stimulus effects of the 1.0 mg/kg training dose of methamphetamine at doses of 5.6–10.0 mg/kg.”
“ Methamphetamine (0.75 mg/kg, IP)-induced mydriasis was similarly inhibited by idazoxan (1 mg/kg, IP) and yohimbine (1 mg/kg, IP).”
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