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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Methamphetamine and Vitamin E

supplement:

Vitamin E

Research Papers that Mention the Interaction

As methamphetamine-induced neurotoxicity has been proposed to involve oxidative stress, reduced and oxidized glutathione (GSH and GSSG, respectively), vitamin E and ascorbate were measured in the striata of rats killed 2 or 24 h after a neurotoxic regimen of methamphetamine.
European journal of pharmacology  •  2000  |  View Paper
methamphetamine (dose range 6.25-25.0 mg/kg) caused long-lasting depletions of dopamine and serotonin … antioxidants, ascorbic acid (10-100 mg/kg), ethanol (1 g/kg), mannitol (2 g/kg), or vitamin E (2 g/kg), attenuated these depletions, whereas … (200-400 mg/kg) exacerbated the depletions.
Neuropharmacology  •  1989  |  View Paper