supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Methamphetamine
supplement:
Sulforaphane
Research Papers that Mention the Interaction
“In models of neurotoxicity, SFN has been shown to suppress neurotoxicity induced by a wide range of toxic factors, such as hydrogen peroxide, prion protein, hyperammonemia, and methamphetamine.”
Effects of sulforaphane in the central nervous system“In addition, the lowering of DA levels and DOPAC as well as DAT immunoreactivity in the striatum, usually seen after repeated administration of METH , was significantly attenuated by both pretreatment and the subsequent administration of SFN.”
“It is of interest to determine whether SFN can attenuate behavioral and neuropathological changes associated with METH exposure.”
“The development of behavioral sensitization after repeated administrations of METH (3 mg/kg/day, once daily for 5 days) was significantly reduced by pretreatment with SFN (10 mg/kg).”
Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback