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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methamphetamine
supplement:
Selenium
Research Papers that Mention the Interaction
“Additionally, we observed an increased generation of reactive oxygen species with methamphetamine exposure in media with 0 nM selenium , which was ameliorated by selenium supplementation.”
Methamphetamine decreases levels of glutathione peroxidases 1 and 4 in SH-SY5Y neuronal cells: protective effects of selenium.“The supplementation of Se attenuated the formation of 3-NT in the striatum resulting from METH treatment.”
Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation“In conclusion, we have shown that dietary Se attenuated methamphetamine neurotoxicity and that this protection involves GPx-mediated antioxidant mechanisms.”
“Both groups significantly reduced methamphetamine use (mean [ SE ] reduction of 7.3 [1.2]) days for placebo, 6.8 [1.2] for NAC) but NAC did not reduce days of methamphetamine use more than placebo (group difference of 0.5 days, 97.5% CI -3.4–4.3).”
N-acetylcysteine (NAC) for methamphetamine dependence: A randomised controlled trial“The essential trace element selenium mitigates methamphetamine-induced neurotoxicity.”
“It seems that selenium had the potential value to alleviate the volume of cystine crystal.”
“ Selenium may inhibit organization of crystal stone , growth and stone aggregation.”
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