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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Methamphetamine
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“ METH increased the levels of 3‐nitrotyrosine in the striatum and this increase was significantly attenuated by pretreatment with a selective neurokinin‐1 receptor antagonist.”
Connection between the Striatal Neurokinin‐1 Receptor and Nitric Oxide Formation during Methamphetamine Exposure“An immunohistochemical study showed that methamphetamine increased 3-nitrotyrosine immunoreactivity, an in vivo marker of peroxynitrite production, and activated microglia and astrocytes in the striatum.”
“Administration of METH resulted in the significant formation of 3-nitrotyrosine (3-NT), an in vivo marker of peroxynitrite generation, in the striatum and also caused a significant increase in the body temperature.”
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