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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Methadone and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

Quinidine increased (P < ….05) plasma methadone concentrations during the absorptive phase, decreased t(max) (2.4 +/- 0.7 vs 1.6 +/- 0.9 h (0.33, 1.2)), and increased peak miosis (3.2 +/- 1.5 vs 4.3 +/- 1.6 mm (-1.96, -0.19)) after oral methadone.
British journal of clinical pharmacology  •  2004  |  View Paper
The transport of methadone was increased in presence of P‐gp inhibitors verapamil and quinidine.
Fundamental & clinical pharmacology  •  1999  |  View Paper