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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Methacholine and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

At the end of the light on period corresponding … peak of the circadian rhythm in ACTH, administration of rMCH but not NEI leads … a decrease in ACTH levels while MCH is not effective during the light off period … the cycle (i.e. when basal ACTH levels are already low).
Taken together, these data indicate that rMCH may act as a central corticotropin inhibitory factor involved in the circadian rhythmicity of plasma ACTH levels and that NEI antagonizes its action.
rMCH (63 or 210 nmoles) prevents the rise in ACTH release while NEI alone does not modify the stress response.
Journal of neuroendocrinology  •  1995  |  View Paper