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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Metformin and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

As for hOCT2-mediated uptake, the IC(50) values of quinidine and the I(f) channel inhibitor for metformin uptake were lower than those for MPP uptake.
Xenobiotica; the fate of foreign compounds in biological systems  •  2008  |  View Paper
The apical uptake of 100 µm metformin in Caco‐2 cells grown on plastic dishes was inhibited significantly by 1 mm unlabeled metformin, quinidine and pyrilamine, indicating that a specific transport system is involved in the apical uptake of metformin in Caco‐2 cells.
Biopharmaceutics & drug disposition  •  2011  |  View Paper
Quinidine , a known inhibitor of organic cation transporters, can significantly affect MET uptake by T. latifolia roots with inhibition ratios of 70-74%.
Chemosphere  •  2015  |  View Paper