supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Metformin
supplement:
Polyunsaturated Fatty Acids
Research Papers that Mention the Interaction
“ Metformin caused qualitative changes in visceral fat composition of HFD mice, with decreased proportions of polyunsaturated fatty acids (14.6% ± 2.3% compared with 17.9% ± 3.0%, P=0.04).”
Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis.“ResultsAll measured PUFAs were significantly increased after treatment with insulin analogs plus metformin compared to before treatment levels.”
“ω-3 PUFAs possess synergistic cardioprotection when added to metformin , suggested by improvements in myocardial ultrastructure, autophagic activity, and SQSTM1 gene expression.”
Effects of omega-3 fatty acids and metformin combination on diabetic cardiomyopathy in rats through autophagic pathway: Effects of omega-3 fatty acids and metformin combination on diabetic cardiomyopathy: Role of autophagy.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback