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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Mersalyl
supplement:
Polypeptides
Research Papers that Mention the Interaction
“Thus, the modification with mersalyl of sulfhydryls of platelet polypeptides along with changes in Ca2+ concentrations within a physiological range leads to changes in solubility of, and filament formation of, myosin, actin and other cytoskeletal proteins.”
Mersalyl, a sulfhydryl reagent, alters the solubility of myosin and cytoskeletal proteins of human platelets.“Generation of these polypeptides in lysates was prevented either by chelation of Ca2+ with EGTA or by the addition of N-ethylmaleimide, leupeptin, or mersalyl , inhibitors of the calcium-dependent protease.”
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