Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“ NADH oxidation, both in intact and in water-treated mitochondria, is 90% inhibited by mersalyl , an inhibitor of the outer membrane NADH-cytochrome b5 reductase, and 10% inhibited by rotenone.”
“4) It is concluded that the inhibition of NADH oxidation of NADH oxidation by superoxide ions or by mersalyl is reversible and is therefore not due to the loss of oxidoreduction components from the respiratory chain or to an irreversible change in protein conformation. (”