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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Mephenytoin
supplement:
Phenethyl Isothiocyanate
Research Papers that Mention the Interaction
“Paclitaxel 6alpha-hydroxylase activity … 100 microM. PEITC noncompetitively inhibited S-warfarin … +/- 0.9 microM), S-mephenytoin 4'-hydroxylase activity catalyzed by CYP2C19 (K(i) = 12.0 +/- 3.2 microM), bufuralol 1'-hydroxylase activity … microM), and chlorzoxazone 6-hydroxylase activity catalyzed by CYP2E1 (K(i) = 21.5 +/- 3.4 microM).”
Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate.
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