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Last Updated: 3 years ago

Possible Interaction: Meperidine and Tubocurarine

supplement:

Tubocurarine

Research Papers that Mention the Interaction

Sub-effective inhibitory concentrations of pethidine and droperidol, and those of tubocurarine , pancuronium and suxamethonium, independently of the sequence of their administration, mutually increased the myoneural effects of one another.
The inhibition caused by the combination of pethidine with tubocurarine or pancuronium was partially antagonized by neostigmine or 4-aminopyridine.(ABSTRACT TRUNCATED AT 250 WORDS)
Tubocurarine antagonized the augmentation of the twitch by pethidine only during indirect stimulation.
British journal of anaesthesia  •  1984  |  View Paper
When epps were recorded in the presence of d-tubocurarine , the percentage depression of epp amplitude by meperidine was significantly greater than found in the presence of Mg++ and was partially antagonized by naloxone indicating an opiate receptor mediated effect of meperidine.
Archives internationales de pharmacodynamie et de therapie  •  1982  |  View Paper