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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Meperidine
supplement:
Oxytocin
Research Papers that Mention the Interaction
“ Pethidine consumption in oxytocin treated group was higher (41 mg vs 89 mg, p = 0.04).”
[Comparison of vaginal misoprostol and oxytocin for labor induction in post-term pregnancy].“Alfentanyl (10(-5) M), meperidine (10(-5) M), remifentanyl (10(-4) M), bupivacaine (10(-4) M), ropivacaine (10(-4) M) and midazolam (3 x 10(-5) M) caused significant decreases in contractile responses of uterine strips to oxytocin.”
The effects of opioids, local anesthetics and adjuvants on isolated pregnant rat uterine muscles.“In addition, however, pethidine depresses the oxytocin responsiveness both of mammary myoepithelium and of myometrium.”
“Thus pethidine inhibits oxytocin secretion in all three conditions; this inhibition is probably mediated by central opioid receptors.”
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