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“ Tocotrienols influenced cholesterol synthesis by directly regulated activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductae ( HMG CoA reductase) and decreased cholesterol.”
Journal of the American College of Nutrition • 1991 | View Paper
“Concomitantly, d-δ-tocotrienol dose-dependently inhibited glucose uptake by 3T3-F442A cells and the expression of GLUT4, HMG CoA reductase, and p-Akt proteins.”