supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Melphalan
supplement:
Resveratrol
Research Papers that Mention the Interaction
“ RSV potentiated the cytotoxic effects of MEL in human breast cancer cells.”
“The activity of CDK7, kinase that phosphorylates CDK2 at Thr160, was inhibited by RSV and by the combination of RSV with MEL.”
“The aim of this study was to investigate whether RSV would be able to enhance the antitumor effects of MEL in MCF‐7 and MDA‐MB‐231 cells.”
“The expression of cyclin A was decreased by treatment with RSV and by the combination of RSV with MEL.”
“These results indicate that RSV could be used as an adjuvant agent during breast cancer therapy with MEL.”
“While the levels of cyclin dependent kinase 2 (CDK2) remained unchanged by treatments, its active form (Thr160‐phosphorylated CDK2) was decreased by treatment with RSV and by the combination of RSV with MEL.”
Resveratrol chemosensitizes breast cancer cells to melphalan by cell cycle arrest
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback