Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Melatonin and Tramadol

supplement:

Melatonin

Research Papers that Mention the Interaction

Intraoperative fentanyl usage, pain scores, and tramadol consumption were significantly lower in the melatonin group (P < 0.05).
The sedation scores were significantly higher in the melatonin group than in the control … at 1 h and 2 h after surgery (P < 0.05).ConclusionsPreoperative oral melatonin administration decreased pain scores and tramadol consumption and enhanced sleep quality, sedation scores, and subjective analgesic efficacy during the postoperative period.
Journal of Anesthesia  •  2010  |  View Paper
Treatment with Lagenaria siceraria or melatonin after tramadol administration for a long-term, markedly changed the collagen content and other chemical components, that may reach nearly normal levels.
Microscopy and Microanalysis  •  2021  |  View Paper
Conclusion Considering the protective effects of MT against reproductive toxicity induced by tramadol , this compound can be used as a possible agent for the prevention and treatment of tramadol-induced reproductive toxicity.
Addiction & health  •  2020  |  View Paper