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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Melatonin
drug:
Thiopental
Research Papers that Mention the Interaction
“Oral premedication with 0.2 mg/kg melatonin significantly reduces the propofol and thiopental doses required for loss of responses to verbal commands and eyelash stimulation.”
Melatonin and anesthesia: a clinical perspective“CONCLUSIONS Melatonin premedication significantly decreased the doses of both propofol and thiopental required to induce anesthesia.”
“… Melatonin … thiopental ED50 values for loss of response to verbal command and eyelash reflex from 3.4 mg/kg (95%confidence interval, 3.2–3.5 … mg/kg (2.6–2.9 mg/kg) and 2.6 mg/kg (2.5–2.7 mg/kg), respectively (P < 0.05).”
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