supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Melatonin
supplement:
S-Adenosylmethionine
Research Papers that Mention the Interaction
“These results suggest an age-related increase in mitochondria vulnerability to oxidation in SAM mice at 10 months of age that was counteracted by melatonin therapy.”
Improved mitochondrial function and increased life span after chronic melatonin treatment in senescent prone mice“These results document an age-related decrease in hepatic mitochondrial function in SAM which can be modified by an acute pharmacological injection of melatonin ; the indole stimulated mitochondrial respiratory chain activity which would likely reduce deteriorative oxidative changes in mitochondria that normally occur in advanced age.”
“The hypothesis that the effect of SAMe on the serotonergic system may be secondary to an increase in brain melatonin is discussed.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback