Possible Interaction: Melatonin and Psychotropic Drugs

“Antidepressants and other psychotropic drugs modify melatonin synthesis.”

“As proposed pineal hormone melatonin may to participate in chronotropic and specific activity of some psychotropic drugs.”

“Antidepressants and some other psychotropic drugs affect the synthesis and release of melatonin through several mechanisms.”

“The continuous increase of use of melatonin in children, often concomitant with other psychotropic medications , together with a high proportion of younger children with prescriptions of melatonin on a long-term basis, suggests the need for further structured follow up studies, in particular of long-term use.”