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Discover Supplement-Drug Interactions

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Last Updated: 19 days ago

Possible Interaction: Melatonin and Polyethylene Glycol 400

Research Papers that Mention the Interaction

The brain (olfactory bulb) levels of MT after intranasal administration were 9.22, 6.77 and 4.04-fold higher for carbopol, CMC and PEG400 , respectively, than that of intravenous MT in rats.
Journal of drug targeting  •  2011  |  View Paper
During seedling growth, soluble protein was involved in osmotic adjustment and superoxide dismutase (SOD) activity was increased to mitigate the damage in the cytomembrane of JM 22 leaf under 300 μmol L-1 melatonin plus PEG treatment.
Lysine (Lys) content in wheat seeds under the PEG plus 300 μmol L-1 melatonin treatment increased compared with that of the seeds under PEG alone.
PloS one  •  2020  |  View Paper
Seeding priming with melatonin significantly increased the germination rate, coleoptile length, and primary root number of wheat under PEG stress, as well as the fresh weight, dry weight, and water content of wheat seedlings.
Under PEG stress, melatonin significantly improved reactive oxygen species homeostasis, as revealed by lower H2O2 and O2· content; and the expression of antioxidant enzymes at the transcription and translation levels was increased.
Planta  •  2018  |  View Paper