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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Melatonin and Ornithine, (L)-Isomer

Research Papers that Mention the Interaction

The results revealed that dim light melatonin onset, a recognized marker of central circadian phase, was delayed by 15 min after ingestion of L-ornithine.
Chronobiology international  •  2018  |  View Paper
Additionally, l-ornithine (1000 mg/kg) administered at ZT22 advanced the onset of the nocturnal rise of melatonin , which resulted in the elongation of the melatonin peak.
In conclusion, our data suggest that a daily administration of l-ornithine regulates the diurnal rhythms of GH, melatonin , and corticosterone in a manner dependent on administration time, which might be related to the diurnal rhythms of l-ornithine metabolism.
Chronobiology international  •  2015  |  View Paper