“Additionally, l-ornithine (1000 mg/kg) administered at ZT22 advanced the onset of the nocturnal rise of melatonin , which resulted in the elongation of the melatonin peak.”
“In conclusion, our data suggest that a daily administration of l-ornithine regulates the diurnal rhythms of GH, melatonin , and corticosterone in a manner dependent on administration time, which might be related to the diurnal rhythms of l-ornithine metabolism.”