“After treatment with omeprazole plus melatonin (group B) or Trp (group C), plasma melatonin levels rose several‐fold above initial values.”
“Plasma gastrin level also rose significantly during treatment with omeprazole plus melatonin or Trp, but it was also significantly increased in patients treated with omeprazole plus placebo.”
“We conclude that melatonin or Trp, when added to omeprazole treatment, accelerates ulcer healing and this likely depends mainly upon the significant increments in plasma melatonin.”