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Last Updated: 2 years ago

Possible Interaction: Melatonin and Oleic Acid

supplement:

Melatonin

supplement:

Oleic Acid

Research Papers that Mention the Interaction

Melatonin inhibits lipid accumulation induced by oleic acid overload in HepG2 cells.
Cell Biochemistry and Biophysics  •  2018  |  View Paper
Melatonin in nanomolar concentrations inhibited oleic acid-induced triglyceride accumulation.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2007  |  View Paper
Using oil red O staining, it was found that when oleic acid was present in the culture media, melatonin at doses of 0.1-2mM, significantly increased the lipid concentrations in the cells.
Neuro endocrinology letters  •  2006  |  View Paper
Meanwhile, similar to saturated lauric acid (C12), unsaturated oleic acid (C18) dramatically enhanced the skin permeability coefficient of MT more than 950-fold over the effect of PG alone.
The results suggest that oleic acid in a suitable vehicle could more effectively enhance the skin permeation of MT and shorten its lag time than did the vehicles of various compositions.
International journal of pharmaceutics  •  2001  |  View Paper