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Last Updated: 3 years ago

Possible Interaction: Melatonin and Nialamide

supplement:

Melatonin

Research Papers that Mention the Interaction

In rodents, monoamine oxidase (MAO) inhibitors (e.g. pheniprazine, harmine or nialamide ) increase pineal concentrations of the melatonin precursors, serotonin (5HT) and N-acetyl serotonin (NAS), by enhancing N-acetyl transferase activity.
Drug metabolism and drug interactions  •  1990  |  View Paper
3e) As with serotonin, microinjections of melatonin into the lateral ventricle performed at the same time as subcutaneous injections of nialamide are followed by a significant decrease of hypothalamic RF content.
As with serotonin, microinjections of melatonin into the lateral ventricle performed at the same time as subcutaneous injections of nialamide are followed by a significant decrease of hypothalamic RF content.
Journal of Neural Transmission  •  2005  |  View Paper
In fact, daytime concentrations of melatonin both in the gland and in serum were significantly increased after either acute or repeated treatment with nialamide.
Repeated administration of either desmethylimipramine or nialamide reduced significantly the elevation in melatonin concentrations in the pineal gland produced by either L-isoproterenol or darkness.
The Journal of pharmacology and experimental therapeutics  •  1982  |  View Paper