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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
Research Papers that Mention the Interaction
“In conclusion, melatonin inhibits nicotinic currents through non‐α7 heteromeric nAChRs expressed by CGNs in culture, an effect that appears to be at least partially mediated by melatonin membrane receptors.”
Melatonin inhibits nicotinic currents in cultured rat cerebellar granule neurons“ Nicotinamide but not 3-amino benzamide prevented the enhancement by melatonin of GTP gamma 35S binding.”
“However, melatonin (30-3000 microM) reversibly decreased the amplitude of nicotinic excitatory postynaptic potentials (EPSPs) in a concentration-dependent manner (IC50 = 247 microM).”
“In voltage-clamp experiments, using the whole-cell configuration, melatonin also inhibited the nicotinic inward currents induced by acetylcholine (IACh) in a concentration-dependent manner (IC50 = 257 microM).”
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