Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Melatonin and Naloxone

supplement:

Melatonin

Research Papers that Mention the Interaction

In the presence of naloxone , the GH response to MEL was completely abolished, whereas naloxone did not modify the pyridostigmine-induced GH increase.
Metabolism: clinical and experimental  •  1998  |  View Paper
Although melatonin is not regulated as a drug, it may interact with benzodiazepines, be antagonized by naloxone and flumazenil, and interact with melatonin receptors in the central nervous system and elsewhere in the body.
Southern medical journal  •  1997  |  View Paper
Melatonin did not affected LH serum levels, while it was able to reduce LH increase induced by naloxone.
Journal of endocrinological investigation  •  1988  |  View Paper
Administration of both l-arginine and naloxone , at doses which produced no effect on their own, partially reversed antihyperalgesic effect of melatonin.
Life sciences  •  2006  |  View Paper
The LH concentration measured during the combined infusion of melatonin and naloxone was significantly higher than that during vehicle infusion.
Acta neurobiologiae experimentalis  •  2005  |  View Paper
The enhancing effects of MT on the phagocytosis can be prevented by naloxon.
Yao xue xue bao = Acta pharmaceutica Sinica  •  2000  |  View Paper
An intraventricular treatment with melatonin , which did not affect the basal LH concentration by itself, significantly suppressed the effect of naloxone.
Endocrine journal  •  1999  |  View Paper
While the antinociceptive effect of melatonin was sensitive to reversal by naloxone (2 mg/kg), other CNS depressant profile resembled the effects of benzodiazepines.
Indian journal of experimental biology  •  1998  |  View Paper
Melatonin (10 ng) also significantly reduced the effect of naloxone.
Journal of neuroendocrinology  •  1997  |  View Paper
Subcutaneous melatonin injection (1.4 mg/Kg) had no effect on LH secretion, but caused an inhibition effect (84%) on LH release induced by naloxone (2.4 mg/Kg).
Journal of endocrinological investigation  •  1996  |  View Paper
Show More