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Last Updated: 2 years ago

Possible Interaction: Melatonin and Nalmefene

supplement:

Melatonin

Research Papers that Mention the Interaction

Melatonin alone had no significant effect on serum PRL levels, but decreased by 25.5% the inhibitory effect potency of nalmefene on PRL secretion after simultaneous injections.
Melatonin too totally inhibited LH secretion induced by naloxone methyliodide (2.8 mg/Kg) and nalmefene (2 mg/Kg) when it was simultaneously administered with each opioid receptor antagonist.
Journal of endocrinological investigation  •  1996  |  View Paper
Subcutaneous melatonin injection (1.4 mg/Kg) had no significant effect on serum PRL levels, but decreased by 29% and 26% respectively the inhibitory effect potency of naltrexone (2.5 mg/Kg) and nalmefene (2 mg/Kg) on PRL secretion after simultaneous injections.
Endocrine research  •  1995  |  View Paper