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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Melatonin enhanced NAD+ and decreased cADP-ribose in the cells, in a CTX independent pathway, indicating inhibition of nicotinamide adenine dinucleotide glycohydrolase (NADase).”
A role for NAD+ and cADP-ribose in melatonin signal transduction“During DPCs differentiation, 10 nM melatonin could significantly induce the increase of intracellular Adenosine triphosphate (ATP), the decrease of the oxidized form of nicotinamide adenine dinucleotide (NAD+)/NADH ratio and reactive oxygen species (ROS).”
Melatonin regulates mitochondrial function and biogenesis during rat dental papilla cell differentiation.“ Melatonin reduced the IL-1β-increased nicotinamide phosphoribosyltransferase (NAMPT) expression and the NAD+ level in chondrocytes in a Sirt1-dependent manner.”
Melatonin inhibits Sirt1-dependent NAMPT and NFAT5 signaling in chondrocytes to attenuate osteoarthritis“ Melatonin reduced the IL-1β-increased nicotinamide phosphoribosyltransferase (NAMPT) expression and the NAD+ level in chondrocytes in a Sirt1-dependent manner.”
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