Possible Interaction: Melatonin and Glycolic Acid

“Combinations … or melatonin … glycolic acid , in a 1:5 to 1:200 molar ratio, resulted in a clear synergistic protection of liposomes, more evident for the combination … with vitamin E. An amount of synergism up to 250% and up to 80% was evahmted with vitamin E and melatonin, respectively.”

“Synergistic antioxidant activity between vitamin E and glycolic acid was also observed in skin homogenates, whereas the effect of glycolic acid on the antioxidant activity of melatonin appeared additive.”