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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Although L-glutamate at 1 mM caused 90% inhibition of melatonin synthesis, about 30% of the NAT activity remained, suggesting the presence of another target for L-glutamate.”
Hydroxyindole-O-methyltransferase is another target for l-glutamate-evoked inhibition of melatonin synthesis in rat pinealocytes“ l-Glutamate is a negative regulator of melatonin synthesis through a metabotropic receptor-mediated inhibitory cAMP cascade.”
“These results suggest that pinealocytes use L-aspartate, as well as L-glutamate , as a negative regulator for melatonin production.”
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