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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Melatonin
drug:
Atorvastatin
Research Papers that Mention the Interaction
“These data suggest that melatonin improves the beneficial effects of atorvastatin and reduces its side effects in endothelial cells during inflammation and under conditions of oxidative stress.”
“Together, melatonin + atorvastatin induced higher eNOS protein expression than either compound alone.”
Synergism between melatonin and atorvastatin against endothelial cell damage induced by lipopolysaccharide“In addition, a combination therapy of MT plus ATO enhanced the beneficial effects of ATO, while not changing the effects of MT effects or even improving them.”
“The present study indicates that a combination therapy of MT plus ATO can attenuate renal injury in rats treated with GEN, possibly by reducing oxidative stress, and it seems that MT can enhance the beneficial effects of ATO.”
Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney.
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