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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Melatonin and Anakinra

supplement:

Melatonin

Research Papers that Mention the Interaction

Melatonin decreased LPS-induced expression of pro-inflammatory cytokines, chemokines, and positive acute-phase proteins (APPs), including tumor necrosis factor-α, interleukin (IL)-1β, … (CCL)2, CCL5, serum amyloid A, haptoglobin, C-reactive protein, ceruloplasmin, and α-1 antitrypsin, and increased expression of the anti-inflammatory cytokine IL-1Ra ….
PloS one  •  2017  |  View Paper
In conclusion, MT can upregulate IL-1Ra gene expression by reducing generation of IL-1 thus reducing IRI.
Biomedical reports  •  2016  |  View Paper