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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Melatonin and 5-Methoxypsoralen

Research Papers that Mention the Interaction

5-methoxypsoralen (5-MOP), a serotonin analogue, stimulates the secretion of melatonin , which plays an important role in circadian rhythm regulation.
Life sciences  •  1993  |  View Paper
Our main finding is that 5MOP specifically stimulates melatonin secretion in humans, with a pronounced effect when administered during the dark phase of the day (at 2100 h).
The Journal of clinical endocrinology and metabolism  •  1990  |  View Paper
5-methoxypsoralen (5-MOP) stimulates pineal melatonin secretion, and a decrease in dark phase melatonin levels has been described in major depression.
European psychiatry : the journal of the Association of European Psychiatrists  •  1995  |  View Paper