Possible Interaction: Melarsoprol and Selenium

“Furthermore, the capability of TMA and MAP to enhance the biliary and total excretion of selenium renders these drugs significant candidates for antidotes in selenium intoxication.”

“The most dramatic alterations included the approximately … in the biliary excretion rate of selenium in … and MAP , the almost complete cessation of the exhalation of selenium as dimethyl selenide after administration of the … gold-containing drugs, and the manifold accumulation of selenium in the blood plasma following gold injection.”